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Thread: Glucosamine

  1. #1

    Default Glucosamine

    Is it safe to take glucosamine while breast feeding. ??

  2. #2
    Join Date
    Oct 2012
    Posts
    2,214

    Default Re: Glucosamine

    InfantRisk can give you good advice about medications (prescription and OTC) while breastfeeding, they have a number you can call:
    www.infantrisk.com

  3. #3
    Join Date
    May 2008
    Location
    SW Ohio
    Posts
    1,626

    Default Re: Glucosamine

    The following information is from Dr. Hale's "Medications and Mothers' Milk." Please do not take my response as medical advice It would be wise to take this information and discuss it with your healthcare provider or pharmacist before using.

    GLUCOSAMINE

    Uses: Antiarthritic

    LRC: L3

    AAP: Not reviewed

    Glucosamine is an endogenous amino monosaccharide that has been reported effective in resolving symptoms of osteoarthritis. It is one of the salt forms of the amino sugar glucosamine, which is a constituent of cartilage proteoglycans. Administered in large doses, most is sequestered in the liver with only minimal amounts reaching other tissues, thus oral bioavailability is low. Most of the oral dose is hepatically metabolized and subsequently incorporated into other plasma proteins.[1] No data are available on transfer into human milk. Because glucosamine is primarily sequestered and metabolized in the liver, and because the plasma levels are almost undetectable, it is unlikely that any would enter human milk. Further, the fact that it is so poorly bioavailable, it is unlikely that an infant would absorb clinically relevant amounts. Do not use with warfarin, as INR levels may double causing an increased risk of bleeding complications.

    Pregnancy Risk Category: C, C

    Lactation Risk Category: L3
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