Let me say that my baby doesn't have reflux, but I was diagnosed with it after I had her. I don't like taking medications for it, BUT I do. Because having GERD is really incredibly painful. For me it feels like a burning sensation in the pit of my stomach on my sides and in my throat. I obviously can't say what it feels like for a tiny baby, but for me the pain is so awful that I cannot even bear the thought of it. It's just so horrid and searing. I even went to the ER once because I thought maybe my appendix was bursting. If my baby had GERD, based on my own experience, I wouldn't hesitate to try the meds. They are like a lifesaver for me. FWIW...