Well, if the pain is resolving, I think that would be an indication there is no infection, or it has cleared up. I understand you are using a nipple sheild but, at least with thrush, isn't the nipple pain usually present even when baby is not nursing? That was my understanding?
No harm in continuing to use APNO as long as it is healing, since that has both anti fungal and antibiotic in it. As far as the nystatin suspension, I think its fine to have baby take that while you are treated with fluconazole, but according to BAMS it's much less effective than fluconazole. So if you suspect thrush again, maybe try to have baby prescribed a fluconazole suspension. Many moms do not like treating thier babies but if it is thrush it is unfortunately neccesary to treat baby as well. Remember that continuing to be able to breastfeed has so many health benefits it is worth it to get proper treatment for both of you when something is interfering with your comfort when nursing.
I am curious, does the blister appear white, (consistent with a bleb) or as if it is more clear (like a friction blister would look?)
It may be a good idea to see your LC again and have her observe a nursing session to see if there is anything you might be able to do differently in terms of postitioning or latch to help prevent more of these ,particularly if it being caused more by friction than a plug?
There are more things you can do for blebs than warm compresses. See this article for more ideas: http://www.llli.org/docs/00000000000...plugsblebs.pdf
joes.mom, I found that info in BAMS interesting too. I don't think the point was that yeast infections never cause such symptoms, but rather that it is more rare than was once thought. This would be consitent with the fact thrush is overdiagnosed in general, which certainly does not mean some moms don;t have struggles with thrush.Thrush can get in the breast (it did for me, or at least, that's what I thought it was, and it seemed to respond to treatment?) where it can cause burning shooting pains at letdown. Not fun. ETA: Reading Meg's description that this is usually Raynaud's or bacterial, but I don't think I had either of those. I guess it's hard to say, but my issue resolved with treatment for thrush.